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We want to know if a DNA sequence is enriched in A. We calculate the proportion of A’s and compare it to the proportion of A’s in a random DNA sequence:
Hypotheses H0: p = 0.25 vs. Ha: p ≠ 0.25
The statistical test generates a p-value = 0.068
What conclusion should be made using α=0.05 ?
What does this conclusion mean?
If you set the significance level to 0.1 instead of 0.05 would that change your conclusion?
I want to check if a DNA sequence is random. I count the number of As, Cs, Gs and Ts:
A C G T
74 95 92 99 Total=360
Which test should I use to check if the sequence is random?
There’s 1 group of data: what you have observed. In the chi square test you have to compare what you have observed to what you expect.
A C G T
observed 74 95 92 99 Total=360
What is the expected count of As ?
The chi square test gives a p-value of 0.005
At α=0.05 what should you conclude?
What is your conclusion in normal words?